SubtiBank SubtiBank
Version comparison:

2018-05-27 12:19:052025-05-31 10:42:57

description

bacillithiol-S-transferase; confers resistence against antimicrobial compounds from B. amyloliquefaciens

bacillithiol-S-transferase; confers resistence against antimicrobial compounds from B. amyloliquefaciens

locus

BSU17840

BSU_17840

geneLength

432

435

function

confers resistence against antimicrobial compounds from B. amyloliquefaciens

confers resistence against antimicrobial compounds from B. amyloliquefaciens

ec

outlinks

bsu

BSU17840

BSU_17840

Gene

Coordinates

1,916,663 → 1,917,097

1,916,663 1,917,097

The protein

Protein family

FosB subfamily (according to Swiss-Prot)

fosfomycin resistance protein family (single member, according to UniProt)

Biological materials

Mutant

MGNA-B387 (yndN::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1386 NBRP B. subtilis, Japan]

BKE17840 (Δ[[gene|fosB]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE17840 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACAAATCATTCCCCCCTTG, downstream forward: _UP4_TGATAGCACAACCATATTTC

BKK17840 (Δ[[gene|fosB]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK17840 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACAAATCATTCCCCCCTTG, downstream forward: _UP4_TGATAGCACAACCATATTTC

MGNA-B387 (yndN::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1386 NBRP B. subtilis, Japan]

BKE17840 ([[gene|fosB]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE17840 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACAAATCATTCCCCCCTTG, downstream forward: _UP4_TGATAGCACAACCATATTTC

BKK17840 ([[gene|fosB]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK17840 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACAAATCATTCCCCCCTTG, downstream forward: _UP4_TGATAGCACAACCATATTTC

Gene

Phenotypes of a mutant

sensitive to fosfomycin [pubmed|11244082]

The protein

Paralogous protein(s)

[[this]]

The protein

[SW|Domains]

[SW|VOC domain] (aa 5-120) (according to UniProt)

The protein

[SW|Cofactors]

Mg2+ [pubmed|11244082]

The protein

Structure

[PDB|4JD1] (from B. anthracis, 66% identity)